It occurs in about 5% of patients who have cardiac surgery, with symptoms of pericarditis from three
weeks to six months after surgery. It is initially treated with NSAIDs and systemic steroids in refractory
Pericardiectomy is rarely required. It is said to result from an autoimmune response and is most
likely to be related to surgical trauma and irritation of blood products in the mediastinum and pericardium.